Yes, but your tv 2 will probably be offline if the 722s 2 tv locations are connected via a diplexer system. If you are not familiar with using diplexers or don't have access to any, you can do a direct backfeed from the home distribution port on the back of the receiver to the tv 2. Meaning, run a cable directly from the receiver to the tv2 if aesthetically feasible. Or turn your receiver into single mode from the mode button inside the front right panel and utilize the PIP functions on one tv.